Molecular Formula | C8H9N5 |
Molar Mass | 175.19 |
Density | 1.39±0.1 g/cm3(Predicted) |
Boling Point | 415.6±48.0 °C(Predicted) |
Solubility | DMSO: ≥ 31 mg/mL |
pKa | 4.08±0.10(Predicted) |
Storage Condition | -20℃ |
Physical and Chemical Properties | Bioactive (Z)-9-Propenyladenine is a mutagenic impurity in tenofovir disoproxil fumarate. Tenofovir is an antiretroviral drug and an inhibitor of nucleotide analog reverse transcriptase (NtART), which can block the reverse transcriptase of HIV-1 and HBV. |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 5.708 ml | 28.54 ml | 57.081 ml |
5 mM | 1.142 ml | 5.708 ml | 11.416 ml |
10 mM | 0.571 ml | 2.854 ml | 5.708 ml |
5 mM | 0.114 ml | 0.571 ml | 1.142 ml |
Biological activity | (Z)-9-Propenyladenine is a mutagenic impurity in tenofovir disoproxil fumarate. Tenofovir is an antiretroviral drug and an inhibitor of nucleotide analog reverse transcriptase (NtART), which can block the reverse transcriptase of HIV-1 and HBV. |